Abstract
Tails of D-dimer Levels and It’s Association with the Clinical Outcome in COVID-19 Patients
Manisha Khandait*
Corresponding Author: Manisha Khandait, Private Medical College & Research Center, Shree Guru Gobind Singh Tricentenary University, Budhera Gurgaon, India
Revised: December 12, 2020; Available Online: December 21, 2020
Citation: Khandait M. (2020) Tails of D-dimer Levels and It’s Association with the Clinical Outcome in COVID-19 Patients. J Infect Dis Res, 3(S3): 13.
Copyrights: ©2020 Khandait M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Introduction: Elevated or abnormal levels of coagulation parameters indicate thrombotic disorders which need to be managed at the earliest to prevent the complications and reduce the mortality in COVID-19 patients. D-dimer is a fibrin degradation product test used as a supportive diagnostic modality for thrombotic disorders. Higher D-dimer levels are a strong indicator of mortality in active COVID-19 cases. This study is aimed to know the relation between D-dimer levels and clinical outcomes of COVID-19 patients.

Materials and Methods: This is a prospective observational study done from April 2020 to September 2020. All the patients with COVID-19 infection were included in this study and their D-dimer levels were estimated.

Results: Patients with higher D-dimer levels, pre-existing disease with increased D-dimer levels had increased hospital stay and increased complications when compared to the patients without pre-existing disease

Conclusion: Abnormally elevated D-dimer levels were frequently observed at admission with COVID-19 and are associated with higher incidence of critical illness, thrombotic events, acute kidney injury, and death.

Keywords: COVID-19, Corona Virus, D-Dimer, Hypercoagulation, Prognosis, Mortality